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Cayman Chemical p120CATnInCTerm RabbIt 100uL
SDP

Supplier:  Cayman Chemical 32283100 UL

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An MTH1 inhibitor (IC50 72 nM) selective for MTH1 over a panel of 456 kinases at 1 UM induces oxidative DNA damage and apoptosis in SGC-7901 and BGC-823 cancer cells at 30 UM induces ROS production and apoptosis in the same model inhibits proliferation in a panel of 14 cancer cell lines expressing wild-type or various mutant forms of K-Ras or p53 (IC50s 0.52-7.4 UM) inhibits tumor growth in an SW 480 mouse xenograft model at 25 mg/kg

Catalog No. 50-295-0473


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