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Apexbio Technology LLC P7C3 301353-96-8 10mg
Supplier: Apexbio Technology LLC B602810
P7C3 is an orally bioavailable neuroprotective small molecule targeting nicotinamide phosphoribosyltransferase (NAMPT) the rate-limiting enzyme in the NAD salvage pathway that converts nicotinamide into NAD It is designed to activate NAMPT thereby facilitating NAD replenishment and preserving mitochondrial function P7C3 exerts its biological activity primarily through NAMPT activation-mediated restoration of intracellular NAD levels In in vitro experiments P7C3 at nanomolar concentrations preserves mitochondrial membrane potential and promotes neuronal survival Based on these pharmacological properties P7C3 holds research potential in neuroprotection and cognitive improvement in preclinical models of neurodegeneration and Down Syndrome
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