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Apexbio Technology LLC PAC-1 315183-21-2 250mg
Supplier: Apexbio Technology LLC A8177250
PAC-1 (CAS 315183-21-2) is a small molecule activator of procaspase-3 promoting its conversion to active caspase-3 through time-dependent cleavage This direct activation of caspase-3 leads to rapid induction of apoptosis in cancer cell lines The compound s pro-apoptotic effect has been shown to correlate with intracellular procaspase-3 levels and its ability to induce cell death displays IC50 values ranging from 0 003 to 1 41 M in early-stage colon cancer isolates compared to higher IC50 values in adjacent normal tissues PAC-1 serves as a valuable tool for investigating apoptosis mechanisms and caspase-3-associated anticancer strategies
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