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AdipoGen Paclitaxel

Supplier: AdipoGen AGCN20045M005

Chemical. CAS 33069-62-4. Formula C47H51NO14. MW 853.9. Isolated from the bark of the pacific yew tree Taxus brevifolia. Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposis sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase. Apoptosis inducer through aberrant activation of cyclin-dependent kinases CKDs and the c-Jun N-terminal kinase/stress activated protein kinase JNK/SAPK. Immunosuppressor. Immunostimulant. Antiproliferative agent for the prevention of restenosis. TRAIL sensitizer
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