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Medchemexpress LLC Palbociclib hydrochloride (PD-0332991 hydrochloride) | 571189-11-2 | 100.0% | 500 MG
SDP

Catalog No. 5000358337
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Palbociclib (PD 0332991) hydrochloride is an orally active, selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. It exhibits potent anti-proliferative activity and is known to induce cell cycle arrest in cancer cells. This compound can be utilized in research related to HR-positive and HER2-negative breast cancer, as well as hepatocellular carcinoma.

  • Orally active selective CDK4 and CDK6 inhibitor.
  • Exhibits potent anti-proliferative activity.
  • Induces cell cycle arrest in cancer cells.
  • Can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.
  • Inhibits retinoblastoma phosphorylation at Ser795.
  • Arrests MDA-MB-453 cells exclusively in G1 phase.

Catalog No. 50-003-58337 Supplier Medchemexpress LLC Supplier No. HY50767C500MG
May include imposed supplier surcharges.
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Palbociclib (PD 0332991) hydrochloride is an orally active, selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. It exhibits potent anti-proliferative activity and is known to induce cell cycle arrest in cancer cells. This compound can be utilized in research related to HR-positive and HER2-negative breast cancer, as well as hepatocellular carcinoma.

  • Orally active selective CDK4 and CDK6 inhibitor.
  • Exhibits potent anti-proliferative activity.
  • Induces cell cycle arrest in cancer cells.
  • Can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.
  • Inhibits retinoblastoma phosphorylation at Ser795.
  • Arrests MDA-MB-453 cells exclusively in G1 phase.

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