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Apexbio Technology LLC Palifosfamide,5mg CAS# 31645-39-3
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Supplier:  Apexbio Technology LLC A36965

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Palifosfamide is the active moiety of ifosfamide (IFA) [1].IFA is alkylating agents which are active against a variety of pediatric sarcomas such as rhabdomyosarcoma (RMS), Ewing’s sarcoma (ES), osteosarcoma (OS) and other undifferentiated soft tissue sarcomas [1].In human OS cell lines SaOS-2, OS229 and OS230, Palifosfamide lysine has broad activity with IC50 ranging from 2.25 to 6.75 μM. While OS222 had the IC50 of 31.5 μM [1].In CB17 female SCID mice, palifosfamide lysine (100 mg/kg) administered intravenously for three consecutive days, the mean weight loss was less than 15% and complete recovery to baseline within 4 weeks of treatment. Other sizes are also available. Please inqury us for quote.

Catalog No. 50-224-0261


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