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Medchemexpress LLC Paliperidone (9-Hydroxyrisperidone) | 144598-75-4 | 99.4% | C23H27FN4O3 | 200 MG
Supplier: Medchemexpress LLC HYA0019200MG
Paliperidone (9-Hydroxyrisperidone) is the major active metabolite of Risperidone, functioning as a dopamine D2 and 5-HT2A antagonist. It also exhibits antagonist activity at α1 and α2 adrenergic receptors and H1-histaminergic receptors, demonstrating efficacy as an antipsychotic agent against schizophrenia.
- Major active metabolite of risperidone
- Dopamine D2 antagonist
- 5-HT2A antagonist
- Antagonist at α1 and α2 adrenergic receptors
- Antagonist at H1-histaminergic receptors
- Effective antipsychotic agent against schizophrenia
- For research use only
- Increases caspase-3 activity in neuroblastoma cells
- May modulate Akt1/GSK3β pathway to protect SK-N-SH cells from glutamate damage
- Can protect SK-N-SH cells from apoptosis induced by glutamate
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