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Apexbio Technology LLC Palonosetron HCl 135729-62-3 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B22295.1
Palonosetron hydrochloride (CAS 135729-62-3) is a selective antagonist of the serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor By inhibiting 5-HT3 receptor-mediated signaling on vagal nerve terminals in the gastrointestinal tract and the central nervous system palonosetron attenuates the emetic response triggered by chemotherapeutic agents It is widely utilized in research focused on the mechanisms underlying chemotherapy-induced nausea and vomiting (CINV) as well as in the evaluation of antiemetic interventions targeting serotonergic pathways
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