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Medchemexpress LLC Palonosetron hydrochloride | 135729-62-3 | 99.94% | C19H25ClN2O | 1 ML
Supplier: Medchemexpress LLC HYA002110MM/1ML
Palonosetron hydrochloride is a 5-HT3 antagonist primarily used to prevent acute, delayed, and overall chemotherapy-induced nausea and vomiting. It also exhibits moderate anti-flavivirus activity and potent anti-Zika virus activity in mammalian cells, and possesses antidepressant activity.
- 5-HT3 antagonist
- Prevents acute, delayed, and overall chemotherapy-induced nausea and vomiting
- Exhibits moderate anti-flavivirus activity
- Possesses potent anti-Zika virus activity in mammalian cells
- Possesses antidepressant activity
- Inhibits enhancement effect of 5-HT on substance P (SP)-induced calcium release in NG108-15 cells
- Reduced immobility in Swiss albino mice
- Dose-dependently inhibited SP-mediated neuronal responses in the Cisplatin-induced rat emesis model
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