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Cayman Chemical PalonsetronhydrochlorIde 50mg
SDP

Catalog No. 502965631
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A 5-HT3 receptor antagonist (Ki = 0.04 nM); selective for 5-HT3 over 5-HT1A, 5-HT1D, 5-HT2A, and 5-HT2C receptors (Kis = ≥15.85 μM for all), as well as a panel of additional neurotransmitter receptors; inhibits 5-HT-induced contraction in isolated guinea pig ileum; inhibits cisplatin-induced emesis in ferrets (ID50 = 1.1 μg/kg, i.v.); inhibits emesis induced by cisplatin, dacarbazine, actinomycin D, and mechlorethamine in dogs (ID50s = 1.9, 4.1, 4.9, and 4.4 μg/kg, respectively)

Catalog No. 50-296-5631 Supplier Cayman Chemical Supplier No. 1675250 MG
May include imposed supplier surcharges.
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A 5-HT3 receptor antagonist (Ki = 0.04 nM); selective for 5-HT3 over 5-HT1A, 5-HT1D, 5-HT2A, and 5-HT2C receptors (Kis = ≥15.85 μM for all), as well as a panel of additional neurotransmitter receptors; inhibits 5-HT-induced contraction in isolated guinea pig ileum; inhibits cisplatin-induced emesis in ferrets (ID50 = 1.1 μg/kg, i.v.); inhibits emesis induced by cisplatin, dacarbazine, actinomycin D, and mechlorethamine in dogs (ID50s = 1.9, 4.1, 4.9, and 4.4 μg/kg, respectively)

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