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Cayman Chemical PAMAM DendrImR G4 0 AmIdoeth
SDP

Supplier:  Cayman Chemical 39113500 MG

Encompass_Preferred

An inhibitor of SUMO-activating enzyme (IC50s 0.003 and 0.011 UM with SUMO1 or SUMO2 respectively as the ubiquitin-like proteins) selective for SAE over NAE and UAE (IC50s 32 and 100 UM respectively) decreases global SUMOylation in HCT116 cells (EC50 0.019 UM) as well as decreases the viability of MDA-MB-468 and A375 cells (EC50s 0.06 and 0.45 UM respectively) reduces tumor growth in an HCT116 mouse xenograft model at 150 and 200 mg/kg twice per day

Catalog No. 50-291-7103


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