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Cayman Chemical PAMAM DendrImR G4 0 SuccInam
Supplier: Cayman Chemical 39121500 MG
A succinamic acid-terminated PAMAM dendrimer; has been used as a drug delivery system in vitro and in vivo; ~45 Å in diameter in PBS and has 64 surface groups; inhibits plaque formation induced by MERS-CoV in infected Vero cells at 10 µM; active against S. aureus; lipid-dendrimer hybrid nanoparticles containing PAMAM G4.0-SAH and encapsulating vancomycin are active against S. aureus and MRSA; PAMAM G4.0-SAH conjugated to Neu5Ac prevents infection by the influenza A subtype H3N2 in a mouse model of pneumonitis at 9 UG/g
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