Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Cayman Chemical PAMAM DendrImR G4 5 Carboxyl
Supplier: Cayman Chemical 39109500 MG
A carboxylate-terminated PAMAM dendrimer; has been used in a drug delivery system; ~87.9 in diameter in water and has 96 surface groups; Unlike PAMAM G5.0, it does not rupture bilayer lipid membranes at 50 µM; PAMAM G4.5 carboxylate disulfur-linked aggregates encapsulating ferulic acid and paclitaxel induce apoptosis and decrease the mitochondrial membrane potential in multidrug-resistant KB-8-5 cancer cells at 10 UG/ml; complexes of PAMAM G4.5 carboxylate with the active component of cisplatin are cytotoxic to A2780 cancer cells (IC50 = 620 nM); a fluorescently labeled form of PAMAM G4.5 carboxylate selectively accumulates in tumors and kidneys over liver, spleen, heart, and lungs in a 4T1 murine mammary carcinoma model
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?