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Cayman Chemical PAMAM DndrImR G6 0 ScInam 50mg
SDP

Supplier:  Cayman Chemical 3912350 MG

Encompass_Preferred

A negative allosteric modulator of mGluR5 binds to mGluR5 (Ki 35.6 nM) selective for mGluR5 over a panel of 116 additional receptors at 10 UM inhibits quisqualate-induced calcium mobilization and inositol phosphate accumulation in HEK293 cells expressing human mGluR5 (IC50s 7 and 5.9 nM respectively) reduces immobility time in the forced swim test in rats at 10 and 30 mg/kg has anxiolytic-like activity in rats inhibits surgical sciatic nerve constriction-induced cold allodynia in rats at 0.1-10 mg/kg increases the threshold of bladder filling volume to trigger the micturition reflex in anesthetized rats

Catalog No. 50-291-6131


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