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Apexbio Technology LLC Pamidronate Disodium 57248-88-1 10mM (in 1mL H2O)

Supplier: Apexbio Technology LLC A24565.1
Pamidronate Disodium (CAS 57248-88-1) is a small-molecule inhibitor targeting osteoclastic bone resorption It is designed to inhibit osteoclast-mediated bone degradation thereby regulating bone metabolism Pamidronate Disodium exerts its biological activity primarily through selective binding to hydroxyapatite crystals in bone followed by suppression of osteoclast activity and induction of osteoclast apoptosis In in vitro studies Pamidronate Disodium demonstrates inhibitory activity on osteoclastic bone resorption with an IC50 in the micromolar range (varying according to experimental conditions) Based on these pharmacological properties Pamidronate Disodium holds research potential in studies of bone density disorders osteoporosis hypercalcemia of malignancy and metastatic bone diseases
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