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Medchemexpress LLC Pamoic acid | 130-85-8 | 99.7% | 388.38 | 10 G
SDP

Catalog No. 5000451598
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Pamoic acid (Embonic acid) is a potent GPR35 agonist with an EC50 of 79 nM. It exhibits neuroprotective and anti-inflammatory properties.

  • Potent GPR35 agonist with an EC50 of 79 nM.
  • Exhibits neuroprotective and anti-inflammatory properties.
  • Activates GPR35, which may increase the phosphorylation of ERK1/2, initiating an anti-inflammatory signal by suppressing NF-κB-dependent inflammatory genes.
  • Has neuroprotective activity in a mouse model of stroke, reducing infarct size in a GPR35 dependent manner.
  • Pamoic acid treatment results in a preferential increment of noninflammatory Ly-6CLo monocytes/macrophages in the ischemic brain along with reduced neutrophil counts.

Catalog No. 50-004-51598 Supplier Medchemexpress LLC Supplier No. HYW00861310G
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Pamoic acid (Embonic acid) is a potent GPR35 agonist with an EC50 of 79 nM. It exhibits neuroprotective and anti-inflammatory properties.

  • Potent GPR35 agonist with an EC50 of 79 nM.
  • Exhibits neuroprotective and anti-inflammatory properties.
  • Activates GPR35, which may increase the phosphorylation of ERK1/2, initiating an anti-inflammatory signal by suppressing NF-κB-dependent inflammatory genes.
  • Has neuroprotective activity in a mouse model of stroke, reducing infarct size in a GPR35 dependent manner.
  • Pamoic acid treatment results in a preferential increment of noninflammatory Ly-6CLo monocytes/macrophages in the ischemic brain along with reduced neutrophil counts.

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