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Medchemexpress LLC Pamoic acid | 130-85-8 | 99.7% | 388.38 | 25 G
SDP

Supplier:  Medchemexpress LLC 25GHYW008613

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Pamoic acid (Embonic acid) is a potent GPR35 agonist with an EC50 of 79 nM. It exhibits neuroprotective and anti-inflammatory properties.

  • Potent GPR35 agonist (EC50 of 79 nM).
  • Exhibits neuroprotective properties.
  • Exhibits anti-inflammatory properties.
  • Reduces infarct size in a mouse model of stroke.
  • Increases noninflammatory Ly-6CLo monocytes/macrophages and reduces neutrophil counts in the ischemic brain.
  • GPR35 activation may increase ERK1/2 phosphorylation, initiating an anti-inflammatory signal by suppressing NF-κB-dependent inflammatory genes.

Catalog No. 50-004-51410


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