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ABclonal Technology Pan Lactic acid-Lysine
Supplier: ABclonal Technology A23004100UL
Histone lysine lactation (Kla) is a newly discovered histone modification that regulates gene expression in macrophages In M1 macrophages lactic acid is derived from incompletely oxidized glucose and then produces lactyl-CoA which is transferred via acetyltransferase p300 to the lysine tail of the histone This modification is abundant in gene promoter regions that lack acetylation and are associated with gene expression activation
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