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CPC Scientific H-Gly-Tyr-Pro-Gly-Gln-Val-OH (trifluoroacetate salt) 5MG
Supplier: CPC Scientific PARP010A
This peptide is the amino terminus of the fourth protease-activated receptor (PAR4) after the cleavage at Arg47/Gly48 was tested for its ability to stimulate COS cells expressing PAR4. The peptide readily activated both wild-type and mutant PAR4 (R47A) at 500 M, whereas thrombin and trypsin only activate the wild-type PAR4.SEQUENCE: H-Gly-Tyr-Pro-Gly-Gln-Val-OH (trifluoroacetate salt)ONE-LETTER SEQUENCE: GYPGQVMOLECULAR FORMULA: C28H41N7O9MOLECULAR WEIGHT: 619.68STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [225779-44-2]SYNONYMS: Proteinase Activated Receptor 4 (1-6) (human), GYPGQV, Thrombin Receptor-Like 3 (1-6) (human), Coagulation Factor II Receptor-Like 3 (1-6) (human)RESEARCH AREA: HematologyREFERENCES:W.-F.Xu et al., Proc. Natl. Acad. Sci. USA, 95, 6642 (1998)H.Andersen et al., Proc. Natl. Acad. Sci. USA, 96, 11189 (1999)R.Kaufmann et al., J. Cancer Res. Clin. Oncol., 126, 91 (2000)SKU(s): PARP-010A, PARP-010B
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