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Cayman Chemical ParecoxIbsodIum salt 10mg
Supplier: Cayman Chemical 2901710 MG
A prodrug form of valdecoxib; converted to valdecoxib by human liver microsomes in vitro and in vivo in rats, dogs, and cynomolgous monkeys; a CB1 agonist (EC50 = 2.4 µM in HEK293 cells); reduces hyperalgesia in a rat model of carrageenan-induced foot pad edema (ED50 = 5 mg/kg) and decreases inflammation in a rat model of M. butyricum-induced arthritis (ED50 = 0.08 mg/kg)
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