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Medchemexpress LLC Paromomycin (sulfate) | 1263-89-4 | 99.9% | 10 G
SDP

Supplier:  Medchemexpress LLC HYB095610G

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Paromomycin (Aminosidine) sulfate is a neomycin derivative, a broad-spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. It functions by prematurely terminating the translation of mRNA and inhibiting protein synthesis through specific binding to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. It is suitable for research concerning bacterial and parasitic infections.

  • Reduces intracellular parasitic forms by 97.2% in Caco-2 cells and by 99.5% in HCT-8 cells against C. parvum forms.
  • Reduces oocysts per gram of feces and intestine in male Swiss albino mice infected with C. parvum.
  • Leads to minimal focal inflammation in the intestines of infected mice.

Catalog No. 50-004-08955


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