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Medchemexpress LLC Paroxetine (hydrochloride) | 78246-49-8 | 100.0% | 1 ML
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Catalog No. 5000406418
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Paroxetine hydrochloride is a potent selective serotonin-reuptake inhibitor and a GRK2 inhibitor with an IC50 of 14 μM. It is used in research for depressive disorders and other biological activities.

  • Potent selective serotonin-reuptake inhibitor
  • GRK2 inhibitor with an IC50 of 14 μM
  • Used for research of depressive disorder
  • Restrains T cell migration induced by CX3CL1
  • Inhibits GRK2 induced activation of ERK
  • Reduces pro-inflammatory cytokines in LPS-stimulated BV2 cells
  • Inhibits LPS-induced nitric oxide production and iNOS expression in BV2 cells
  • Blocks LPS-induced JNK activation
  • Attenuates symptoms of CIA rats and prevents histological damage of joints
  • Reduces myocyte cross-sectional area in rats and ROS formation

Catalog No. 50-004-06418 Supplier Medchemexpress LLC Supplier No. HYB049210MM/1ML
May include imposed supplier surcharges.
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Paroxetine hydrochloride is a potent selective serotonin-reuptake inhibitor and a GRK2 inhibitor with an IC50 of 14 μM. It is used in research for depressive disorders and other biological activities.

  • Potent selective serotonin-reuptake inhibitor
  • GRK2 inhibitor with an IC50 of 14 μM
  • Used for research of depressive disorder
  • Restrains T cell migration induced by CX3CL1
  • Inhibits GRK2 induced activation of ERK
  • Reduces pro-inflammatory cytokines in LPS-stimulated BV2 cells
  • Inhibits LPS-induced nitric oxide production and iNOS expression in BV2 cells
  • Blocks LPS-induced JNK activation
  • Attenuates symptoms of CIA rats and prevents histological damage of joints
  • Reduces myocyte cross-sectional area in rats and ROS formation

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