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Medchemexpress LLC Paroxetine hydrochloride hemihydrate | 110429-35-1 | 100.0% | 100 MG
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Supplier:  Medchemexpress LLC HYB0492A100MG

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Paroxetine hydrochloride hemihydrate is a potent selective serotonin-reuptake inhibitor, commonly prescribed as an antidepressant, and has GRK2 inhibitory ability with an IC50 of 14 μM. This product is intended for research use only.

  • GRK2 inhibition with an IC50 of 14 μM.
  • Restrains T cell migration induced by CX3CL1.
  • Inhibits GRK2-induced activation of ERK and reduces pro-inflammatory cytokines in LPS-stimulated BV2 cells.
  • Attenuates symptoms of CIA rats and prevents histological joint damage.
  • Reduces myocyte cross-sectional area and ROS formation.
  • Decreases susceptibility to ventricular tachycardia and LV remodeling.
  • Attenuates tactile hypersensitivity in CCI models.

Catalog No. 50-004-09282


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