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Enzo Life Sciences Parthenolide (50 mg). CAS: 20554-84-1
Supplier: Enzo Life Sciences BMLT1130050
Sesquiterpene lactone. Widely used as an herbal remedy for arthritis and migraine. Has anti-inflammatory, antisecretory and spasmolytic activity. Specifically inhibits activation of NF-κB by preventing the degradation of IκBα and IκBβ. Inhibits activation of MAP kinase (MAPK/ERK) and generation of leukotriene B4 and thromboxane B2. Potent anticancer agent. Induces apoptosis in various cancer cell lines. Specifically inhibits histone deacetylase 1 (HDAC1) without affecting other class I/II HDACs. Inhibits tubulin carboxypeptidase (TCP) activity. Alternative name: (1aR-[1aR*,4E,7aS*,-10aS*,-10bR*])-2,3-6,7,7a,8,10a,10b-Octahydro-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclo deca[1,2-b]furan-9(1aH)-one. Purity: ≥97% (HPLC, TLC). Solubility: Soluble in DMSO (100mg/ml), dichloromethane (50mg/ml) or 100% ethanol (20mg/ml). Long Term Storage: -20°C.
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