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Medchemexpress LLC Patulin | 149-29-1 | 5 MG
Supplier: Medchemexpress LLC HYN67795MG
Patulin is a mycotoxin produced by fungi including Aspergillus, Penicillium, and Byssochlamys species. It causes chromosome breakage, mutation, teratogenic, and cytotoxic effects. Patulin induces autophagy-dependent apoptosis through the lysosomal-mitochondrial axis and causes DNA damage. This product is for research use only. Store at -20°C, protect from light. When in solvent, store at -80°C for 6 months or -20°C for 1 month, protecting from light.
- Induces autophagy-dependent apoptosis
- Causes DNA damage
- Impairs mitophagy in HepG2 cells
- Increases active cleaved caspase-3 levels
- Increases LC3-II levels
- Reduces intracellular glutathione concentration in vivo
- Increases lipid peroxidation in vivo
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