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Selleck Chemical LLC Pazopanib 25mg 444731-52-6 GW786034

Supplier: Selleck Chemical LLC S301225MG

Pazopanib (GW786034) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms/CSF1R with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively. Pazopanib induces cathepsin B activation and autophagy. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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