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Medchemexpress LLC Pazopanib (GW786034) | 444731-52-6 | MFCD11616589 | 99.9% | 437.52 g/mol | C21H23N7O2S | 200 MG
SDP

Supplier:  Medchemexpress LLC HY10208200MG

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Pazopanib (GW786034) is a small-molecule, multi-target tyrosine kinase inhibitor provided as a research-grade solid. It potently inhibits VEGFR1, VEGFR2, and VEGFR3 and shows activity against PDGFRβ, c-Kit, FGFR1, and c-Fms, with reported IC50 values in the low nanomolar range; it also inhibits VEGF-induced proliferation and VEGFR-2 phosphorylation in HUVEC cells.

  • Multi-target VEGFR/PDGFR tyrosine kinase inhibitor
  • Potent enzyme inhibition with IC50s: VEGFR1 10 nM, VEGFR2 30 nM, VEGFR3 47 nM
  • Cellular activity: inhibits VEGF-induced proliferation and VEGFR-2 phosphorylation (~8 nM)
  • High purity (99.9%) solid suitable for research applications
  • Available in research packaging sizes including 200 mg

Catalog No. 50-002-48484


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