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Medchemexpress LLC PB28 dihydrochloride | 172907-03-8 | 99.6% | 443.49 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY108511100MG

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PB28 dihydrochloride is a high-affinity and selective sigma 2 (σ2) receptor agonist with a Ki of 0.68 nM, also acting as a σ1 antagonist with a Ki of 0.38 nM. This cyclohexylpiperazine derivative inhibits electrically evoked twitch in guinea pig bladder and ileum, and can modulate SARS-CoV-2-human protein-protein interaction. It induces caspase-independent apoptosis and exhibits antitumor activity. This product is for research use only.

  • High-affinity and selective sigma 2 (σ2) receptor agonist
  • Sigma 1 antagonist
  • Inhibits electrically evoked twitch in guinea pig bladder and ileum
  • Modulates SARS-CoV-2-human protein-protein interaction
  • Induces caspase-independent apoptosis
  • Exhibits antitumor activity

Catalog No. 50-003-45243


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