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TARGETMOL CHEMICALS INC PD 151746 25MG

Supplier: TARGETMOL CHEMICALS INC T2493
Also available in 5 mg 10 mg 50 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. PD151746 is a calpain inhibitor with a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 uM) over m-calpain (Ki = 5.33 ± 0.77 uM). Its IC50 values are 0.26 ± 0.03 uM (Ki for u-calpain) and 5.33 ± 0.77 uM (Ki for m-calpain) [1]. In vitro PD151746 targets calpain and reduces oxLDL-induced cytotoxicity [2]. purity: 98%
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