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Cayman Chemical PD 168077maleate 50mg
Supplier: Cayman Chemical 2978950 MG
A dopamine D4 receptor agonist (Ki = 8.7 nM in CHO Pro 5 cells expressing the human receptor); selective for dopamine D4 over D2 and D3 receptors (Kis = 3,740 and 2,810 nM, respectively), as well as α1- and α2-adrenergic and 5-HT1A and 5-HT2A (Kis = 168, 177, 385, and 4,010 nM, respectively); induces CaMKII translocation from the dendritic shaft to postsynaptic sites on the dendritic processes of primary rat embryonic prefrontal cortex pyramidal neurons at 20 µM; induces penile erections in rats from 50-200 ng/animal; increases spontaneous locomotion and reduces grooming and rearing in rats from 0.2-25 mg/kg
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