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AdipoGen PD 184 352

Supplier: AdipoGen AGCR10029M001
Chemical. CAS 212631-79-3. Formula C17H14ClF2IN2O2. MW 478.7. MEK MAPKK inhibitor. Potent and selective MAPK ERK kinase 1 MEK1 activation inhibitor IC50 = 300 nM in vitro, IC50 = 2 nM in vivo. Suppresses activation of MAPK but does not block its activity. Antiproliferative. Causes cell-cycle arrest in G1 phase. Tumor suppressor. Apoptosis inducer.
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