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Cayman Chemical PD-1PD-L1 InhIbItr N11 1mg
Supplier: Cayman Chemical 396631 MG
A PD-1/PD-L1 interaction inhibitor (IC50 = 6.3 nM); increases T cell proliferation in a PD-L1-overexpressing CT26 colon cancer cell and T cell co-culture at 20 nM; promotes T cell infiltration into an in vitro PD-L1-overexpressing murine Lewis lung carcinoma tumor matrix at 20 and 80 nM; reduces tumor growth and promotes CD8+ and CD4+ T cell tumor infiltration in a PD-L1-overexpressing murine Lewis lung carcinoma model at 20 mg/kg
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