Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Abcam PD0332991, Cdk4/Cdk6 inhibitor, 5MG
Supplier: Abcam AB2181185MG
MW 447.5 Da, Purity >98%. Potent, highly specific inhibitor of Cdk4 (IC₅₀ = 11 nM) and Cdk6 (IC₅₀ = 16 nM). Displays selectivity for Cdk4/6 over a panel of 36 additional protein kinases (IC₅₀ values are > 10 μM). Induces G₁ cell cycle arrest and senescence in retinoblastoma protein (Rb)-proficient cell lines. Blocks growth of intracranial glioblastoma multiforme xenografts in mice. Blood-brain barrier permeable.
The product is subject to the following: Abcam Restricted Use Statement
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?