PD1 Detection Set, ProSci

Catalog No.	Quantity
16-595-251	1 Set

Catalog No. 16-595-251 Supplier ProSci LLC Supplier No. SD8600SET

Description

Llama Monoclonal Detection Sets

PD1 Monoclonal specifically detects PD1 in Human samples. It is validated for ELISA

PD-1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of danger signals such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases.

Specifications

• Antigen: PD1
• Applications: ELISA
• Concentration: Antibody 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PD-1 Antibodies are supplied in PBS.
• Host Species: Llama
• Immunogen: PD-1 antibodies were raised against a recombinant protein corresponding to amino acids 25 - 167 of human PD-1.
• Purification Method: PD-1 Antibodies are affinity chromatography purified via Nickel column. Antibodies are supplied as a His-tagged purified protein. They also contains a myc-tag for detection.
• Quantity: 1 Set
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: PD-1 antibodies should be stored in working aliquots at -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Product Type: Detection Sets
• Form: Liquid