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Apexbio Technology LLC PDD00017273, 10mg CAS# 1945950-21-9
SDP

Supplier:  Apexbio Technology LLC B839410

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PDD00017273 is a potent and selective poly (ADP ribose) glycohydrolase (PARG) inhibitor with IC50 of 26 nM and KD value of 1.45 nM. PDD00017273 is 350 times more selective for PARG on a series of ion channels, enzymes and receptors including PARP1 and ARH3.PDD 00017273 (10 M) does not inhibit five common Cytochrome P450 enzymes. PDD 00017273 (30 M) modestly increasess phosphorylated H2AX (H2AX) intensity.PDD 00017273 also decreases in NAD/H activity through PARG inhibition after DNA damage. Other sizes are also available. Please inqury us for quote.

Catalog No. 50-199-8437


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