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Apexbio Technology LLC PDE5-IN-7 139756-21-1 1g
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Catalog No. 5000094911
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PDE5-IN-7 (CAS 139756-21-1) is a selective inhibitor of phosphodiesterase 5 (PDE5) functioning by impeding PDE5 enzymatic activity and thereby reducing the hydrolysis of cyclic guanosine monophosphate (cGMP) This results in elevated intracellular cGMP levels In biochemical assays PDE5-IN-7 demonstrates potent inhibition of PDE5 with an IC50 of approximately 5 nM while displaying significantly lower potency against PDE1 (IC50 300 nM) Due to its selectivity and potency PDE5-IN-7 is valuable for investigating cGMP-mediated signaling vasorelaxation mechanisms and pathways involved in cardiovascular physiology

Catalog No. 50-000-94911 Supplier Apexbio Technology LLC Supplier No. A47121000
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PDE5-IN-7 (CAS 139756-21-1) is a selective inhibitor of phosphodiesterase 5 (PDE5) functioning by impeding PDE5 enzymatic activity and thereby reducing the hydrolysis of cyclic guanosine monophosphate (cGMP) This results in elevated intracellular cGMP levels In biochemical assays PDE5-IN-7 demonstrates potent inhibition of PDE5 with an IC50 of approximately 5 nM while displaying significantly lower potency against PDE1 (IC50 300 nM) Due to its selectivity and potency PDE5-IN-7 is valuable for investigating cGMP-mediated signaling vasorelaxation mechanisms and pathways involved in cardiovascular physiology

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