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Cayman Chemical PDGFR TKI III 5mg

Supplier: Cayman Chemical 149255 MG
A PDGFRα and PDGFRβ inhibitor (IC50s = 0.05 and 0.13 µM, respectively); selective for PDGFRα and PDGFRβ over FGFR, EGFR, PKA, and PKC (IC50s = 29.7, >30, >30, and >30 µM, respectively) but does inhibit c-Kit and FLT3 (IC50s = 0.05 and 0.23 µM, respectively); inhibits PDGF homodimer-induced proliferation of pig aorta smooth muscle cells (IC50 = 0.25 µM); inhibits the migration of primary mouse DA-MSCs induced by embryonic mouse blood at 2 µM
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