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Eurofins Discoverx PDGFRα (550-end, V561D), active, 250 µg. (14-735M)
Supplier: Eurofins Discoverx 14735M
N-terminal 6xHis-tagged recombinant, human PDGFRα amino acids 550-end, containing the V561D mutation. This V561D mutation has been found in some patients with gastrointestinal stromal tumors and confers constitutive activity (Hirota S et al., Gastroenterology (2003); 125:660-667 and Lasota, J. et al., Laboratory Investigation (2004): 84: 874-883). For detailed product information, visit www.discoverx.com/proteins.
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