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Cayman Chemical PDL1CD274CTerm RabbIt M 100uL
Supplier: Cayman Chemical 32252100 UL
A quaternary ammonium-containing cationic surfactant with diverse biological activities an inhibitor of F. tularensis AcpB (Ki 0.59 UM) and C. albicans V-ATPase (EC50 69 UM) inhibits osteoclastogenesis RANKL-induced osteoclastogenesis in BMDMs inhibits bone resorption by mature osteoclasts at 100 and 200 nM prevents LPS-induced bone loss in a calvarial osteolytic mouse model at 5 mg/kg per day induces mortality in C. oncophora O. ostertagi H. contortus and T. circumcincta (EC50s 4.5 10.8 5.1 and 6.7 UM respectively) but is cytotoxic to HEK293 and RAW 264.7 cells (CC50s 9.2 and 5.7 UM respectively)
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