PDL2 Detection Set (Risk Free), ProSci

Catalog No.	Quantity
16-595-771	1 Set

Catalog No. 16-595-771 Supplier ProSci LLC Supplier No. RF16020SET

Description

Mouse Monoclonal Detection Sets

PDL2 Monoclonal specifically detects PDL2 in Human samples. It is validated for ELISA, Western Blot, ICC, IHC-P, Flow, IF

Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PD-L2 can act to stimulate an immunogenic response through an alternative receptor from PD-1. ProSci's Risk-FreeTM antibodies are mouse monoclonal antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, Risk-FreeTM antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. Validated for flow cytometry and ELISA Rigorously tested for the following applications: Immunoblot Immunohistochemistry Immunocytochemistry Immunofluorescence Multiple antibodies per target allowing the user to choose the best antibody for their application Available individually or as a set Risk-FreeTM means they are guaranteed to work for their approved applications

Specifications

• Antigen: PDL2
• Applications: ELISA, Western Blot, Immunocytochemistry, Immunohistochemistry (Paraffin), Flow Cytometry, Immunofluorescence
• Concentration: Antibody 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS containing 0.02% sodium azide.
• Host Species: Mouse
• Immunogen: Mouse monoclonal PD-L2 antibodies were raised against the extracellular domain of human PD-L2.
• Purification Method: Antibodies are supplied as protein A purified IgG1.
• Quantity: 1 Set
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Antibodies can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Product Type: Detection Sets
• Form: Liquid
• Isotype: IgG1