Cytek Biosciences Inc Antibodies PE-Cyanine7 Anti-Mouse CD279 (PD-1) (RMP1-30) ..... Cat. No. 60-9981-U025 ..... Size 25 µg

Supplier:  Cytek Biosciences Inc 609981U025

Antibodies PE-Cyanine7 Anti-Mouse CD279 (PD-1) (RMP1-30) ..... Cat. No. 60-9981-U025 ..... Size 25 µgThe RMP1-30 antibody is specific for mouse CD279, also known as programmed death-1 (PD-1), a 55 kDa glycoprotein member of the Ig superfamily of molecules. PD-1 exists in a monomeric form that is expressed by CD4- CD8- thymocytes, where it participates in the processes of clonal selection, elimination of autoreactive lymphocytes, and development of tolerance. PD-1 expression is also inducible upon activation of mature T cells, where it has been proposed to interact with the co-stimulatory receptor CD80 to limit T cell activation. Two ligands for PD-1, known as PD-L1 (B7-H1) and PD-L2 (B7-DC) are differentially expressed on T and B cells, monocytes, macrophages, NK cells or dendritic cells.

Catalog No. 50-210-3553