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ABclonal Technology PE Rabbit anti-Mouse CD45 mAb
Supplier: ABclonal Technology A26507500T
This gene encodes a protein with heparan sulfate proteoglycan binding heparin binding and protein tyrosine phosphatase activity It plays roles in lymphocyte differentiation regulation of signal transduction and macromolecule metabolism It also regulates lymphocyte activation and protein phosphorylation The protein is found on the external side of the plasma membrane in focal adhesions and membrane rafts It is expressed in various tissues including the branchial arch cardiovascular and hemolymphoid systems and placenta It is studied in systemic lupus erythematosus and is orthologous to human PTPRC linked to hepatitis C multiple sclerosis and forms of severe combined immunodeficiency
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