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Medchemexpress LLC Pefloxacin mesylate | 70458-95-6 | 99.7% | 1 G
Supplier: Medchemexpress LLC HYB0147A1G
Pefloxacin mesylate is a broad-spectrum antibiotic that blocks DNA replication by inhibiting DNA gyrase and DNA relaxation catalyzed by topoisomerase I. It exhibits antibacterial activity against various bacteria such as *Escherichia coli*, *Pseudomonas aeruginosa*, and *Bacteroides fragilis*. It has also shown activity against *Plasmodium yoelii* infection and can increase UVA-induced edema and immunosuppression, making it suitable for infection studies.
- Inhibits DNA replication by blocking DNA gyrase
- Inhibits DNA relaxation catalyzed by topoisomerase I (IC50 of 45 μg/mL)
- Exhibits broad-spectrum antibacterial activity
- Active against *Escherichia coli*, *Pseudomonas aeruginosa*, and *Bacteroides fragilis*
- Demonstrates activity against *Plasmodium yoelii* infection
- Increases UVA-induced edema and immunosuppression
- Suitable for infection studies
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