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Cayman Chemical PEG 2000-C-DMG 10mg
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Supplier:  Cayman Chemical 3714910 MG

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A p38a MAPK inhibitor (IC50 0.019 UM) selective for p38a MAPK over a panel of 10 kinases including ERK2 JNK1 EGFR and C-RAF (IC50s 10 UM for all) inhibits IL-1a-induced production of NO in bovine articular cartilage explants (IC50 ~1 UM) inhibits increases in epidermal COX-2 levels and erythema in mice exposed to UVB irradiation at 100 mg/kg reduces paw edema in a rat model of adjuvant-induced arthritis at 10 30 and 60 mg/kg

Catalog No. 50-291-5372


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