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Medchemexpress LLC Peg4-spdp | 1305053-43-3 | 488.57 g/mol | C20H28N2O8S2 | 250 MG
Supplier: Medchemexpress LLC HY126496250MG
PEG4-SPDP is a cleavable polyethylene glycol (PEG4) spacer variant of the SPDP crosslinker used as an ADC linker and general bioconjugation reagent. It features an N-hydroxysuccinimide (NHS) ester for amine coupling and a 2-pyridyldithiol group for thiol coupling, providing a reducible disulfide linkage for controlled payload release in reducing environments.
- Cleavable disulfide linker for controlled payload release in reducing environments.
- Amine-reactive NHS ester for conjugation to lysine residues.
- 2-pyridyldithiol group for thiol coupling and disulfide bond formation.
- Suitable for antibody-drug conjugates and protein crosslinking.
- Stable as a solid at -20°C; store solutions at lower temperatures for short-term use.
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