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Medchemexpress LLC Pegcetacoplan acetate | 2019171-69-6 | 99.9% | (C2H4O)nC170H248N50O47S4.xC2H4O2 | 5 MG
Supplier: Medchemexpress LLC HYP3252A5MG
Pegcetacoplan acetate is a pegylated inhibitor of complement C3/C3b, specifically binding to and inhibiting C3 and C3b to suppress the complement cascade at its proximal stage. It is not known to inhibit or induce CYP450 isoenzymes. This product is intended for research purposes related to complement-mediated diseases, including paroxysmal nocturnal hemoglobinuria (PNH) and age-related macular degeneration (AMD).
- Targets C3 upstream of C5, providing control over intravascular and extravascular haemolysis
- Inhibits C3 and blocks C3 consumption
- Restores physiological C3 levels
- Leads to significant proteinuria reduction
- Useful for research of complement-mediated diseases like AMD, C3 glomerulopathy, Geographic atrophy (GA), autoimmune haemolytic anaemia, and PNH
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