Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 502950335

Cayman Chemical Pemigatinib, Purity: ≥98%, CAS: 1513857-77-6, 10 mg
SDP

Catalog No. 502950335
Encompass_Preferred

An FGFR inhibitor (IC50s = 0.4, 0.5, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively); selective for FGFR1, FGFR2, and FGFR3 over FGFR4 and KDR (IC50s = 30 and 70 nM, respectively), as well as over a panel of 56 tyrosine and serine/threonine kinases at 10 µM; reduces phosphorylation of FGFR, ERK1/2, and STAT5 in KG-1a acute myeloid leukemia cells in a concentration-dependent manner; inhibits growth in a panel of cancer cell lines expressing constitutively active FGFR (GI50s = 3-362 nM); reduces tumor growth in KATO III, KG-1, and RT-112 mouse xenograft model at 0.3 mg/kg

Catalog No. 50-295-0335 Supplier Cayman Chemical Supplier No. 3326010 MG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

An FGFR inhibitor (IC50s = 0.4, 0.5, and 1 nM for FGFR1, FGFR2, and FGFR3, respectively); selective for FGFR1, FGFR2, and FGFR3 over FGFR4 and KDR (IC50s = 30 and 70 nM, respectively), as well as over a panel of 56 tyrosine and serine/threonine kinases at 10 µM; reduces phosphorylation of FGFR, ERK1/2, and STAT5 in KG-1a acute myeloid leukemia cells in a concentration-dependent manner; inhibits growth in a panel of cancer cell lines expressing constitutively active FGFR (GI50s = 3-362 nM); reduces tumor growth in KATO III, KG-1, and RT-112 mouse xenograft model at 0.3 mg/kg

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.