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Abcam Penitrem A, blocker of KCa1.1, 1MG

Catalog No. 502706414
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MW 634.2 Da, Purity >98%. Potent, selective BKCa blocker (IC₅₀ values are 6 and 60 nM for α-subunit and mixed α- and β₁-subunit containing channels respectively). No effect on native delayed rectifier K+ currents, cloned voltage-dependent Kv₁.₅ channels, or KATP currents. Inhibits BK channels in inside-out and cell-attached patches. Tremorgenic effects and increases total peripheral resistance in vivo. Orally active.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-270-6414 Supplier Abcam Supplier No. AB1418421MG
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MW 634.2 Da, Purity >98%. Potent, selective BKCa blocker (IC₅₀ values are 6 and 60 nM for α-subunit and mixed α- and β₁-subunit containing channels respectively). No effect on native delayed rectifier K+ currents, cloned voltage-dependent Kv₁.₅ channels, or KATP currents. Inhibits BK channels in inside-out and cell-attached patches. Tremorgenic effects and increases total peripheral resistance in vivo. Orally active.

The product is subject to the following: Abcam Restricted Use Statement

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