Apexbio Technology LLC Pentoxyverine Citrate 23142-01-0 10mM (in 1mL DMSO)

Supplier:  Apexbio Technology LLC B18115.1

Pentoxyverine Citrate (CAS 23142-01-0) is a small-molecule antagonist targeting acetylcholine receptors (AChR) including 1 and 2 receptors It acts by inhibiting central and peripheral cholinergic pathways thereby regulating neural control of cough reflex sensitivity Pentoxyverine Citrate exerts its biological activity primarily through suppression of the cough reflex via modulation of sensory nerve pathways It demonstrates antitussive anticonvulsant and antispasmodic activity with K i values of 41 nM for 1 894 nM for 2 and 75 nM for 1 receptors in guinea pig brain membrane models Based on these pharmacological properties Pentoxyverine Citrate holds research potential in studies of cough physiology cholinergic neurotransmission and therapeutic interventions in respiratory conditions

Catalog No. 50-000-96524