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Enzo Life Sciences Pepstatin A (synthetic) (100mg). CAS: 26305-03-3
Supplier: Enzo Life Sciences ALX260085M100
Protease inhibitor. Inhibitor of aspartate (acid) proteases, including pepsin, cathepsin D, renin, chymosin, bacterial aspartic proteinases and HIV proteases. Efficiently inhibits Fcγ receptor induction by IFN-γ. Blocks the endocytic pathway followed by an antibody when it enters the cell at the level of early endosomal compartments, resulting in inhibition of autoantigen presentation or viral transmission. Suppresses p-53-dependent apoptosis in lymphoid cells as well as TNFα-induced apoptosis in U937 cells. Inhibits degradation of autophagic cargo inside autophagolysosomes. Alternative name: Iva-Val-Val-Sta-Ala-Sta, i-Valeryl-L-Val-L-Val-AHMHA-L-Ala-AHMHA. Formula: C34H63N5O9. MW: 685.9. Purity: ≥98% (HPLC). Appearance: White to off-white solid. MI: 14: 7147. Solubility: Soluble in DMSO (10mg/ml), methanol (1mg/ml) or acetic acid. Long Term Storage: -20°C. Use/Stability: Stable for at least 2 years after receipt when stored at -20°C. Handling: Protect from light.
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